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Cinnovex

 

CinnoVex®

Description: Each pre-filled syringe/vial of CinnoVex® containing 30µg (6 Million IU / 0.5 ml-1 ml) recombinant human interferon beta-1a for intramuscular injection, produced under EU GMP license.

INN: Interferon Beta-1a

Indication: Relapsing forms of multiple sclerosis

Protein type: Interferon

Mechanism of action: Interferon beta upregulates the expression of MHC I proteins, allowing for increased presentation of peptides derived from viral antigens. This enhances the activation of CD8+ T cells that are the precursors for cytotoxic T lymphocytes (CTLs) and makes the macrophage a better target for CTL-mediated killing. Whether the mechanism of action of Cinnovex in MS is mediated by the same pathway as the biological effects described above is not known because the pathophysiology of MS is not well established.

CinnoVex Liquid leaflet (PDF)

CinnoVex Lyophilized leaflet (PDF)

ReciGen

ReciGen®

Description: Each pre-filled syringe of ReciGen® containing 44µg (12 Million IU / 0.5 ml) recombinant human interferon beta-1a for subcutaneous injection, produced under EU GMP license.

INN: Interferon Beta-1a 44mcg

Indication: Relapsing multiple sclerosis

Protein type: Interferon

Mechanism of action: Interferon beta upregulates the expression of MHC I proteins, allowing for increased presentation of peptides derived from viral antigens. This enhances the activation of CD8+ T cells that are the precursors for cytotoxic T lymphocytes (CTLs) and makes the macrophage a better target for CTL-mediated killing. The precise mechanism of action of Recigen in multiple sclerosis is still under investigation.

ReciGen leaflet (PDF)

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